منابع مشابه
Medical treatment of hypercalcaemia.
Hypercalcaemia results from the failure of renal calcium excretion to compensate increased influx of calcium into the circulation from the intestine, the kidneys and the skeleton. Hypercalcaemia is a common metabolic abnormality of varying severity that can be adequately diagnosed and treated. Primary hyperparathyroidism and malignant neoplasms are responsible for >90% of all cases. The managem...
متن کاملMithramycin treatment of malignant hypercalcaemia.
Medical Memoranda MnWLJOUL 167 I would like to thank Dr. A. Brown for permission to publish this report and for helpful advice and criticism. My thanks are also due to Dr. George McDonald, who carried out the iliac crest biopsy. Mithramycin is an antibiotic with anti-tumour activity similar to actinomycin D. Hypocalcaemia has been reported following its use (Brown and Kennedy, 1965), and it has...
متن کاملDrugs for the treatment of hypercalcaemia
Hypercalcaemia is ordinarily treated by treatment of the underlying disorder. In some cases, as in malignant disease, in vitamin D poisoning and after a failed parathyroidectomy, the hypercalcaemia itself needs to be treated. A large number of methods have been advocated for this, but phosphate is the drug of choice in most patients. This paper outlines its use, mode of action and side effects ...
متن کاملPhosphate treatment of hypercalcaemia due to carcinoma.
Thirteen patients with hypercalcaemia due to carcinoma received inorganic phosphate, orally or intravenously, as palliative treatment for their high serum calcium levels. The serum calcium promptly fell in all patients fully treated, and there was a striking clinical improvement in most patients. The blood urea was usually unchanged or became nearer to normal, while the serum phosphate altered ...
متن کاملTreatment of immobilization-related hypercalcaemia with denosumab
In this issue, de Beus and Boer [4] report the case of a patient with chronic renal failure and immobilizationrelated hypercalcaemia successfully treated with denosumab after a partial and transient response to pamidronate. The case suggests that denosumab might be a promising alternative to bisphosphonates also for the treatment of resorption-related hypercalcaemia in patients with renal insuf...
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ژورنال
عنوان ژورنال: HORMONES
سال: 2009
ISSN: 1109-3099
DOI: 10.14310/horm.2002.1225